This web page is made up of transient details about bortezomib and a collection of backlinks to far more information regarding the use of this drug, analysis effects, and ongoing medical trials.
chloramphenicol will boost the stage or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Aged: Though facts are lacking, a person should really choose great safety measures when administering bortezomib to seniors due to risk of toxicity. However, the impact of the drug is the same as in young sufferers.
fosaprepitant will increase the level or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
If the feminine is Expecting and it has a lifetime-threatening circumstance, using bortezomib calls for a radical discussion Along with the affected individual, oncologists, and associates of your ethics committee.
tell your medical doctor and Health care provider For anyone who is allergic to bortezomib, mannitol, every other remedies, boron, or any with the ingredients in bortezomib. Check with your Health care provider for an index of the components.
Amyloidosis: Patients with amyloidosis also needs to get bortezomib therapy with wonderful caution as you can find reports that using bortezomib may lead to surplus protein accumulation in many organs.
Developments during the review of macrophage polarization in inflammatory immune skin disorders Tingting Xia
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indinavir will boost the stage or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will reduce the extent or impact of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 Thalicarpine metabolism. CP-866087 Use Caution/Monitor.
stiripentol will increase the level or outcome of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Carefully. Take into account cutting down the dose of CYP2C19 substrates, if adverse reactions are expert when administered concomitantly with stiripentol.
rifapentine will reduce the extent or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
erythromycin stearate will raise the degree or result of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.